Facts & figures.
Germany is the largest market in Europe and a leading economy. It can provide both a large domestic market and easy access to other markets within the European Union. In addition, Germany's highly developed infrastructure easily connects people and goods both within Germany and across the European continent. Germany has a very good climate for innovators; it is Europe's leading patent filer, and German research and development is supported by its government, both financially and regulatory.
Employees in Germany are generally better educated than average, with 81% of the population having a recognized vocational qualification or having obtained a university entrance qualification. Attractive incentives for investors and secure framework conditions for investment as well as competitive tax conditions create a valuable environment for future-proof investments and innovations.
Population: 83.2 mio.
Number of companies: 3.4 mio.
More than 70.000 foreign companies.
Europe's largest & leading economy.
Total GDP 2021: $4226 billion
More than 80% of people have completed higher education.
Europe's leading patent applicant.
Area: 357.000 km2
1160 investment rounds for German startups in 2021.
German startups received 17.4 billion euros in investments in 2021.
Germany is the best location for startups, based on data from the World Bank, UNESCO and other agencies.
Relatively low corporate income tax rates: 15.825 %
Metropolitan Region Rhine-Neckar
Facts & figures.
The Metropolitan Region Rhine-Neckar is located in southwestern Germany. It includes the cities of Heidelberg, Mannheim and Ludwigshafen, among others, and covers an area of 5,600 square kilometers. Around 160,000 companies are located in the region.
The main industries are: Chemicals, Software and Health & Life Sciences. Some well-known international companies such as BASF, Pepperl+Fuchs, Daimler, Roche and SAP have their headquarters and operations in the Rhine-Neckar region.
In addition, there is a rich network for startups. With at least 40 events per year, 5 startup support organisations, and more than 20,000 square meters of office and lab space reserved for startups, support for your business is always nearby.
The metropolitan region, which is spread over three federal states, has around 2,4 million inhabitants. It is also characterized by its strong economy. In 2018, at least 45 companies were reported to be involved in the manufacture of chemical and pharmaceutical products, together responsible for more than 6,000 jobs.
The Metropolitan Region Rhine-Neckar is centrally and conveniently located, both within Germany and in Europe. From the train station in Mannheim, one of the European rail hubs, there is not only a direct train connection to all major German cities, but also to many major European cities.
The high-speed train also takes you to Frankfurt Airport, one of the largest airports in Europe, in just 30 minutes. So you are always quickly at your destination, nationally and internationally.
Frankfurt (30 min)
- Financial services, fintech, cybersecurity
Munich (3 h)
- Automotive, IT, Biotech, Insurance
Ruhr area (Cologne & Düsseldorf) (3 h)
- Chemistry, energy, logistics, steel
Stuttgart (1,5 h)
- Production, sustainability, AI, automotive, IT
Zurich (4 h)
- Financial services, life sciences
Regional ecosystem for startups
Active and lively in the Metropolitan Region Rhine-Neckar.
Corporate & Investment Partners
In addition to startup support partners and events, companies and investors in the Rhine-Neckar region are also willing to cooperate with startups. Many of the largest German companies from the chemical and life sciences sectors as well as companies from the strong German SME sector are based in the Rhine-Neckar region. Research shows that 62 % of regional startups willing to cooperate work with established companies. Another 16 % of these startups work with strategic investors instead of companies.
Also at 5-HT we can help you connect with your potential future German customers & collaboration partners. For startups in our ecosystem, we can organize corporate feedback sessions and other connections with our partners.
Founders and young companies need a network. In the Rhine-Neckar region, many events are planned each year where you can network and meet the people who will help your company move forward. Below, you will find an overview of some partners and events in the region per industry.
- Life Science Accelerator BW
- BioRN Lounge
- BioRN Espresso
- BioRN Annual Conference
- Inspire program
- Pilot Incubator
- Insuring Digital Health
- Mannheim Conference on Energy and the Environment
Municipal Startup Partner
Several partners of 5-HT offer (free) consultations for startups on a variety of topics related to starting and running your business. These partners are located in the main cities of the region, i.e. Mannheim, Ludwigshafen and Heidelberg.
In addition, local chambers of commerce and industry offer free information and advice on:
- Legal and tax consultating
- CE certification
- Technology transfer and IP
- Funding programs
You can find more information about the advisory services offered by the chambers of industry and commerce on their websites: rhein-neckar.ihk24.de and pfalz.ihk24.de. Here it is also possible to register directly for a consultation event.
Startup partner in Mannheim
At STARTUP MANNHEIM you can get individual advice from several experts on what to consider when setting up a company in the region. An association of partners in Mannheim offers vouchers for a free consultation for certain target groups.
Focus on medical technology
There is a large funding infrastructure in Mannheim especially for startups in the field of medical technology. Programs and centers within this infrastructure include:
- Startup Center for Medical Technologies CUBEX41 and Business Development Center CUBEX ONE
- Mannheim Medical Technology Cluster
- Mannheim Medical Technology Campus
- Clinical validation capabilities in the Hybrid OP and INSPIRE platform
- Application Center for Intelligent Machines in Medical Technology (ANIMMED)
- Maximum care hospital University Medicine Mannheim, where CUBEX41 is located
- Life Science Accelerator Baden-Württemberg
- Expert panel offers advisors with decades of experience for every step of a medtech company`s development
- Ready to go sales office Ready to go sales office to keep fixed costs low at the beginning
- Simulation centers (without Hybrid-OP @ CUBEX41)
- Fraunhofer Project Group for Automation in Medicine and Biotechnology
- Forschungscampus Mannheim Molecular Intervention Environment (M²OLIE)
- Institute for Medical Technology at the University of Heidelberg and the Mannheim University of Applied Sciences
- FH Impulse research association M2Aind
- CeMOS – Center for Mass Spectrometry and Optical Spectroscopy
- BADEN-WÜRTTEMBERG Coordination Office for Telemedicine (KTBW)
Spaces and Co-Working Spaces
Together with our shareholders and cooperation partners, we provide over 100,000 square meters of space, divided into co-working spaces, lab, office and event spaces. If that's what you're looking for, you've come to the right place.
Become part of the 5-HT Digital Hub Chemistry & Health
Exchange ideas with innovative startups and future-oriented companies in our ecosystem. We look forward to meeting you!